2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione isolated from Averrhoa carambola L. root ameliorates diabetic nephropathy by inhibiting the TLR4/MyD88/NF-κB pathway

BACKGROUND: Averrhoa carambola L. is a traditional medicinal herb that has long been used to treat diabetes. Our previous studies found that 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD) isolated from A. carambola L. roots could ameliorate diabetic nephropathy (DN), but its exact mechanism...

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Detalles Bibliográficos
Autores principales: Lu, Shunyu, Zhang, Hongliang, Wei, Xiaojie, Huang, Xiang, Chen, Lixiu, Jiang, Luhui, Wu, Xingchun, Zhou, Xing, Qin, Luhui, Li, Yuchun, Lin, Xing, Huang, Renbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689538/
https://www.ncbi.nlm.nih.gov/pubmed/31496773
http://dx.doi.org/10.2147/DMSO.S209436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689538/
https://www.ncbi.nlm.nih.gov/pubmed/31496773
http://dx.doi.org/10.2147/DMSO.S209436

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