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Small vessel disease to subcortical dementia: a dynamic model, which interfaces aging, cholinergic dysregulation and the neurovascular unit

BACKGROUND: Small vessels have the pivotal role for the brain’s autoregulation. The arteriosclerosis-dependent alteration of the brain perfusion is one of the major determinants in small vessel disease. Endothelium distress can potentiate the flow dysregulation and lead to subcortical vascular demen...

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Detalles Bibliográficos
Autores principales: Caruso, Paola, Signori, Riccardo, Moretti, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689673/
https://www.ncbi.nlm.nih.gov/pubmed/31496716
http://dx.doi.org/10.2147/VHRM.S190470