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Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice

BACKGROUND: Postoperative neurocognitive disorder (PND) is a severe postoperative complication with no effective therapy that affects up to 19–52% of senior patients. Age and surgery type have been identified as risk factors. However, what caused the increased risk in the elderly is poorly understoo...

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Detalles Bibliográficos
Autores principales: Zhao, Guangchao, Deng, Jiao, Shen, Yuan, Zhang, Peng, Dong, Hailong, Xie, Zhongcong, Xiong, Lize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689684/
https://www.ncbi.nlm.nih.gov/pubmed/31353838
http://dx.doi.org/10.1002/acn3.50838