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Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome

De novo loss‐of‐function mutations in SCN1A are the main cause of Dravet syndrome, a catastrophic encephalopathy characterized by recurrent early‐life febrile seizures, a number of other afebrile seizure types that are often refractory to treatment, and behavioral abnormalities including social defi...

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Detalles Bibliográficos
Autores principales: Wong, Jennifer C., Thelin, Jacquelyn T., Escayg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689688/
https://www.ncbi.nlm.nih.gov/pubmed/31402621
http://dx.doi.org/10.1002/acn3.50848