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Tying Metabolic Branches With Histone Tails Using Systems Biology
Histone modifications represent an innate cellular mechanism to link nutritional status to gene expression. Metabolites such as acetyl-CoA and S-adenosyl methionine influence gene expression by serving as substrates for modification of histones. Yet, we lack a predictive model for determining histon...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689906/ https://www.ncbi.nlm.nih.gov/pubmed/31448363 http://dx.doi.org/10.1177/2516865719869683 |