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Tying Metabolic Branches With Histone Tails Using Systems Biology

Histone modifications represent an innate cellular mechanism to link nutritional status to gene expression. Metabolites such as acetyl-CoA and S-adenosyl methionine influence gene expression by serving as substrates for modification of histones. Yet, we lack a predictive model for determining histon...

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Detalles Bibliográficos
Autor principal: Chandrasekaran, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689906/
https://www.ncbi.nlm.nih.gov/pubmed/31448363
http://dx.doi.org/10.1177/2516865719869683