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Exosomes regulate neurogenesis and circuit assembly

Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits. We show that exosome treatment increases proliferation in developing neural cultures and in vivo in denta...

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Detalles Bibliográficos
Autores principales: Sharma, Pranav, Mesci, Pinar, Carromeu, Cassiano, McClatchy, Daniel R., Schiapparelli, Lucio, Yates, John R., Muotri, Alysson R., Cline, Hollis T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689941/
https://www.ncbi.nlm.nih.gov/pubmed/31320591
http://dx.doi.org/10.1073/pnas.1902513116