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Novel Cell Wall Antifungals Reveal a Special Synergistic Activity in pbr1 Mutants Resistant to the Glucan Synthesis Antifungals Papulacandins and Echinocandins

A series of 4-(arylmethylene)-3-isochromanones have been prepared with base-catalyzed Knoevenagel condensation starting from 3-isochromanone and aromatic aldehydes. The outcome of the reaction- the isomeric composition of the products depends on the aromatic aldehyde applied. These reactions afforde...

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Detalles Bibliográficos
Autores principales: Berzaghi, Rodrigo, Agócs, Attila, Curto, María A., Gulyás-Fekete, Gergely, Kocsis, Béla, Ribas, Juan C., Lóránd, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689975/
https://www.ncbi.nlm.nih.gov/pubmed/31428061
http://dx.doi.org/10.3389/fmicb.2019.01692