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Liraglutide attenuates cardiac remodeling and improves heart function after abdominal aortic constriction through blocking angiotensin II type 1 receptor in rats

OBJECTIVE: Angiotensin II (Ang II) is known to contribute to the pathogenesis of heart failure by eliciting cardiac remodeling and dysfunction. The glucagon-like peptide-1 (GLP-1) has been shown to exert cardioprotective effects in animals and patients. This study investigates whether GLP-1 receptor...

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Detalles Bibliográficos
Autores principales: Zheng, Rong-Hua, Bai, Xiao-Jie, Zhang, Wei-Wei, Wang, Jing, Bai, Feng, Yan, Cai-Ping, James, Erskine A, Bose, Himangshu S, Wang, Ning-Ping, Zhao, Zhi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690048/
https://www.ncbi.nlm.nih.gov/pubmed/31496651
http://dx.doi.org/10.2147/DDDT.S213910