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Poly(lactic-co-glycolic acid) nanoparticle-mediated interleukin-12 delivery for the treatment of diabetic retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a complication of diabetes that affects the eyes and vision. It is a leading cause of visual impairment and blindness in working-age people. Vascular endothelial growth factor-A (VEGF-A) is a primary initiator and potential mediator of DR. Matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Zeng, Lina, Ma, Wenbei, Shi, Lingyu, Chen, Xiaohong, Wu, Rong, Zhang, Yingying, Chen, Huaiwen, Chen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690602/
https://www.ncbi.nlm.nih.gov/pubmed/31496691
http://dx.doi.org/10.2147/IJN.S214727