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AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma

Osteosarcoma is the most common malignant bone tumor in children, adolescents, and young adults. This pleiomorphic tumor depends on new blood vessel development, also known as angiogenesis, for tumor growth and metastasis. Therefore, it’s of utmost importance to identify the key genes and pathways t...

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Detalles Bibliográficos
Autores principales: Al-Khalaf, Huda H., Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690669/
https://www.ncbi.nlm.nih.gov/pubmed/31448053
http://dx.doi.org/10.18632/oncotarget.27115