Cargando…

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma

Osteosarcoma is the most common malignant bone tumor in children, adolescents, and young adults. This pleiomorphic tumor depends on new blood vessel development, also known as angiogenesis, for tumor growth and metastasis. Therefore, it’s of utmost importance to identify the key genes and pathways t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Khalaf, Huda H., Aboussekhra, Abdelilah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690669/ https://www.ncbi.nlm.nih.gov/pubmed/31448053 http://dx.doi.org/10.18632/oncotarget.27115

Ejemplares similares

p16(INK4A) Positively Regulates p21(WAF1) Expression by suppressing AUF1-dependent mRNA decay
por: Al-Khalaf, Huda H., et al.
Publicado: (2013)

AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1
por: AlAhmari, Manar M., et al.
Publicado: (2020)

p16(INK4A) Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1
por: Al-Khalaf, Huda H., et al.
Publicado: (2011)

Effects of siRNA-mediated HIF-1α gene silencing on angiogenesis in osteosarcoma
por: Zhang, Xu-dong, et al.
Publicado: (2017)

HIF-1α increases the osteogenic capacity of ADSCs by coupling angiogenesis and osteogenesis via the HIF-1α/VEGF/AKT/mTOR signaling pathway
por: Song, Shuang, et al.
Publicado: (2023)

NADPH Oxidase 4 Mediates Insulin-Stimulated HIF-1α and VEGF Expression, and Angiogenesis In Vitro
por: Meng, Dan, et al.
Publicado: (2012)

Early missed abortion is associated with villous angiogenesis via the HIF-1α/VEGF signaling pathway
por: Zhi, Zhifu, et al.
Publicado: (2018)

Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
por: Cheng, Jiao, et al.
Publicado: (2019)

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
por: Schipani, Ernestina, et al.
Publicado: (2009)

The p16(INK4a) tumor suppressor controls p21(WAF1) induction in response to ultraviolet light
por: Al-Mohanna, Mai A., et al.
Publicado: (2007)

Houshiheisan promotes angiogenesis via HIF-1α/VEGF and SDF-1/CXCR4 pathways: in vivo and in vitro
por: Xiang, Yangyang, et al.
Publicado: (2019)

Novel Nargenicin A1 Analog Inhibits Angiogenesis by Downregulating the Endothelial VEGF/VEGFR2 Signaling and Tumoral HIF-1α/VEGF Pathway
por: Han, Jang Mi, et al.
Publicado: (2020)

WISP-1 positively regulates angiogenesis by controlling VEGF-A expression in human osteosarcoma
por: Tsai, Hsiao-Chi, et al.
Publicado: (2017)

The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts
por: Hendrayani, Siti-Fauziah, et al.
Publicado: (2016)

Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway
por: Wu, Jianming, et al.
Publicado: (2016)

Dandelion Polysaccharide Exerts Anti-Angiogenesis Effect on Hepatocellular Carcinoma by Regulating VEGF/HIF-1α Expression
por: Ren, Feng, et al.
Publicado: (2020)

Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights
por: Abdalla, Ali, et al.
Publicado: (2022)

CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer
por: Wang, Yu-Zhao, et al.
Publicado: (2023)

The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis
por: Oh, Su Young, et al.
Publicado: (2015)

Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis
por: Kim, Yunho, et al.
Publicado: (2016)

Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma
por: Zhang, Yan, et al.
Publicado: (2017)

Influence of Dll4 via HIF-1α-VEGF Signaling on the Angiogenesis of Choroidal Neovascularization under Hypoxic Conditions
por: Dong, Xiao, et al.
Publicado: (2011)

The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners
por: Zhang, Yanan, et al.
Publicado: (2016)

Gastrin mediates cardioprotection through angiogenesis after myocardial infarction by activating the HIF-1α/VEGF signalling pathway
por: Wang, Rui, et al.
Publicado: (2021)

Rivastigmine Regulates the HIF-1α/VEGF Signaling Pathway to Induce Angiogenesis and Improves the Survival of Random Flaps in Rats
por: Liu, Yingying, et al.
Publicado: (2022)

Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors
por: Casillas, Andrea L., et al.
Publicado: (2021)

High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients
por: Al-Tweigeri, Taher, et al.
Publicado: (2022)

Ionizing radiation normalizes the features of active breast cancer stromal fibroblasts and suppresses their paracrine pro-carcinogenic effects
por: Aboussekhra, Abdelilah, et al.
Publicado: (2023)

Pien Tze Huang Inhibits Hypoxia-Induced Angiogenesis via HIF-1α/VEGF-A Pathway in Colorectal Cancer
por: Chen, Hongwei, et al.
Publicado: (2015)

Leonurine Improves Age-Dependent Impaired Angiogenesis: Possible Involvement of Mitochondrial Function and HIF-1α Dependent VEGF Activation
por: Qi, Jia, et al.
Publicado: (2017)

HIF-1α and HIF-2α induced angiogenesis in gastrointestinal vascular malformation and reversed by thalidomide
por: Feng, Nan, et al.
Publicado: (2016)

Expression of VEGF, its receptors, and HIF-1α in Dupuytren’s disease
por: Holzer, Lukas A, et al.
Publicado: (2013)

Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway
por: ZENG, ZHI, et al.
Publicado: (2015)

Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway
por: Zeng, Zhi, et al.
Publicado: (2023)

Association of Dll4/Notch and HIF-1a -VEGF Signaling in the Angiogenesis of Missed Abortion
por: Fang, Yan, et al.
Publicado: (2013)

KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma
por: Shen, Mao, et al.
Publicado: (2023)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Effect of tetramethylpyrazine on tibial dyschondroplasia incidence, tibial angiogenesis, performance and characteristics via HIF-1α/VEGF signaling pathway in chickens
por: Mehmood, Khalid, et al.
Publicado: (2018)

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling
por: Liu, Peng, et al.
Publicado: (2017)

Tibial dyschondroplasia is highly associated with suppression of tibial angiogenesis through regulating the HIF-1α/VEGF/VEGFR signaling pathway in chickens
por: Huang, Shu-cheng, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_b1nf1s95jidc54legh32ih5hap