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(Pro)renin receptor contributes to renal mitochondria dysfunction, apoptosis and fibrosis in diabetic mice

Recently we demonstrated that increased renal (Pro)renin receptor (PRR) expression in diabetes contributes to development of diabetic kidney disease. However, the exact mechanisms involving PRR activity and diabetic kidney dysfunction are unknown. We hypothesized that PRR is localized in renal mitoc...

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Detalles Bibliográficos
Autores principales: Li, Caixia, Matavelli, Luis C., Akhtar, Safia, Siragy, Helmy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690878/
https://www.ncbi.nlm.nih.gov/pubmed/31406124
http://dx.doi.org/10.1038/s41598-019-47055-1