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(Pro)renin receptor contributes to renal mitochondria dysfunction, apoptosis and fibrosis in diabetic mice
Recently we demonstrated that increased renal (Pro)renin receptor (PRR) expression in diabetes contributes to development of diabetic kidney disease. However, the exact mechanisms involving PRR activity and diabetic kidney dysfunction are unknown. We hypothesized that PRR is localized in renal mitoc...
Autores principales: | Li, Caixia, Matavelli, Luis C., Akhtar, Safia, Siragy, Helmy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690878/ https://www.ncbi.nlm.nih.gov/pubmed/31406124 http://dx.doi.org/10.1038/s41598-019-47055-1 |
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