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Neurotoxic potential of reactive astrocytes in canine distemper demyelinating leukoencephalitis
Canine distemper virus (CDV) causes a fatal demyelinating leukoencephalitis in young dogs resembling human multiple sclerosis. Astrocytes are the main cellular target of CDV and undergo reactive changes already in pre-demyelinating brain lesions. Based on their broad range of beneficial and detrimen...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690900/ https://www.ncbi.nlm.nih.gov/pubmed/31406213 http://dx.doi.org/10.1038/s41598-019-48146-9 |