Cargando…

Neurotoxic potential of reactive astrocytes in canine distemper demyelinating leukoencephalitis

Canine distemper virus (CDV) causes a fatal demyelinating leukoencephalitis in young dogs resembling human multiple sclerosis. Astrocytes are the main cellular target of CDV and undergo reactive changes already in pre-demyelinating brain lesions. Based on their broad range of beneficial and detrimen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klemens, J., Ciurkiewicz, M., Chludzinski, E., Iseringhausen, M., Klotz, D., Pfankuche, V. M., Ulrich, R., Herder, V., Puff, C., Baumgärtner, W., Beineke, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690900/ https://www.ncbi.nlm.nih.gov/pubmed/31406213 http://dx.doi.org/10.1038/s41598-019-48146-9

Ejemplares similares

Reactive Oxygen Species Are Key Mediators of Demyelination in Canine Distemper Leukoencephalitis but not in Theiler’s Murine Encephalomyelitis
por: Attig, Friederike, et al.
Publicado: (2019)

Transcriptional Changes in Canine Distemper Virus-Induced Demyelinating Leukoencephalitis Favor a Biphasic Mode of Demyelination
por: Ulrich, Reiner, et al.
Publicado: (2014)

New Aspects of the Pathogenesis of Canine Distemper Leukoencephalitis
por: Lempp, Charlotte, et al.
Publicado: (2014)

Canine Distemper Virus Alters Defense Responses in an Ex Vivo Model of Pulmonary Infection
por: Chludzinski, Elisa, et al.
Publicado: (2023)

Phenotypic and Transcriptional Changes of Pulmonary Immune Responses in Dogs Following Canine Distemper Virus Infection
por: Chludzinski, Elisa, et al.
Publicado: (2022)

Viral Oncolysis — Can Insights from Measles Be Transferred to Canine Distemper Virus?
por: Lapp, Stefanie, et al.
Publicado: (2014)

Accumulation of Extracellular Matrix in Advanced Lesions of Canine Distemper Demyelinating Encephalitis
por: Seehusen, Frauke, et al.
Publicado: (2016)

Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis
por: Spitzbarth, Ingo, et al.
Publicado: (2016)

Overcoming the Barrier of the Respiratory Epithelium during Canine Distemper Virus Infection
por: Shin, Dai-Lun, et al.
Publicado: (2022)

Early and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis
por: Robinson, Christopher A, et al.
Publicado: (2014)

Neuropathologic and molecular aspects of a canine distemper epizootic in red foxes in Germany
por: Geiselhardt, Franziska, et al.
Publicado: (2022)

Cross-species transmission of canine distemper virus—an update
por: Beineke, Andreas, et al.
Publicado: (2015)

Demyelination in canine distemper encephalomyelitis: An ultrastructural analysis
por: Sumummers, Brian A., et al.
Publicado: (1987)

Intratumoral Canine Distemper Virus Infection Inhibits Tumor Growth by Modulation of the Tumor Microenvironment in a Murine Xenograft Model of Canine Histiocytic Sarcoma
por: Armando, Federico, et al.
Publicado: (2021)

Mesenchymal to epithelial transition driven by canine distemper virus infection of canine histiocytic sarcoma cells contributes to a reduced cell motility in vitro
por: Armando, Federico, et al.
Publicado: (2020)

Oxidative Stress in Canine Histiocytic Sarcoma Cells Induced by an Infection with Canine Distemper Virus Led to a Dysregulation of HIF-1α Downstream Pathway Resulting in a Reduced Expression of VEGF-B In Vitro
por: Armando, Federico, et al.
Publicado: (2020)

Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis
por: Machado, Gisele F., et al.
Publicado: (2013)

Distemper in a Dolphin
por: Wohlsein, Peter, et al.
Publicado: (2007)

Canine distemper virus persistence in demyelinating encephalitis by swift intracellular cell-to-cell spread in astrocytes is controlled by the viral attachment protein
por: Wyss-Fluehmann, Gaby, et al.
Publicado: (2010)

Detection of Systemic Canine Kobuvirus Infection in Peripheral Tissues and the Central Nervous System of a Fox Infected with Canine Distemper Virus
por: Kaiser, Franziska K., et al.
Publicado: (2021)

Glial proteins in canine distemper virus-induced demyelination: A sequential immunocytochemical study
por: Vandevelde, M., et al.
Publicado: (1983)

Mesenchymal stem cells in dogs with demyelinating leukoencephalitis as an experimental model of multiple sclerosis
por: Pinheiro, Luane Lopes, et al.
Publicado: (2019)

Canine Distemper
por: Felton, Howard B.
Publicado: (1896)

Canine Distemper Virus Infection Leads to an Inhibitory Phenotype of Monocyte-Derived Dendritic Cells In Vitro with Reduced Expression of Co-Stimulatory Molecules and Increased Interleukin-10 Transcription
por: Qeska, Visar, et al.
Publicado: (2014)

Functional Granulocyte–Macrophage Colony-Stimulating Factor (GM-CSF) Delivered by Canine Histiocytic Sarcoma Cells Persistently Infected with Engineered Attenuated Canine Distemper Virus
por: Marek, Katarzyna, et al.
Publicado: (2023)

Persistent Infection of a Canine Histiocytic Sarcoma Cell Line with Attenuated Canine Distemper Virus Expressing Vasostatin or Granulocyte-Macrophage Colony-Stimulating Factor
por: Marek, Katarzyna, et al.
Publicado: (2022)

Control of canine distemper
por: Chappuis, G.
Publicado: (1995)

Growth of canine distemper virus in cultured astrocytes: relationship to in vivo persistence and disease
por: Pearce-Kelling, Susan, et al.
Publicado: (1990)

Beneficial and Detrimental Effects of Regulatory T Cells in Neurotropic Virus Infections
por: Ciurkiewicz, Malgorzata, et al.
Publicado: (2020)

Transcriptome analysis following neurotropic virus infection reveals faulty innate immunity and delayed antigen presentation in mice susceptible to virus‐induced demyelination
por: Ciurkiewicz, Malgorzata, et al.
Publicado: (2021)

Oligodendroglial pathology in canine distemper
por: Zurbriggen, A., et al.
Publicado: (1997)

Canine distemper : its complications, sequelae, and treatment
por: Kirk, Hamilton
Publicado: (1922)

Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx)
por: Lombardo, Mara Sophie, et al.
Publicado: (2023)

Commentary: SLAM- and Nectin-4-Independent Noncytolytic Spread of Canine Distemper Virus in Astrocytes
por: Di Guardo, Giovanni, et al.
Publicado: (2016)

Porcine Bocavirus Infection Associated with Encephalomyelitis in a Pig, Germany
por: Pfankuche, Vanessa M., et al.
Publicado: (2016)

Phocine Distemper in German Seals, 2002
por: Müller, Gundi, et al.
Publicado: (2004)

Canine Distemper in Endangered Ethiopian Wolves
por: Gordon, Christopher H., et al.
Publicado: (2015)

Primary demyelination in experimental canine distemper virus induced encephalomyelitis in gnotobiotic dogs: Sequential immunologic and morphologic findings
por: Higgins, R. J., et al.
Publicado: (1982)

THE SIMULTANEOUS OCCURRENCE OF THE VIRUSES OF CANINE DISTEMPER AND LYMPHOCYTIC CHORIOMENINGITIS : A CORRECTION OF "CANINE DISTEMPER IN THE RHESUS MONKEY"
por: Dalldorf, Gilbert
Publicado: (1939)

Interferon-Stimulated Genes—Mediators of the Innate Immune Response during Canine Distemper Virus Infection
por: Klotz, Daniela, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k7ruca0hltu3oui5084urlao06