Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis

Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene expression. Among the Rho GTPases, RhoA, Rac1 and Cdc42 are best characterized. The...

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Detalles Bibliográficos
Autores principales: Zahra, Fatema Tuz, Sajib, Md Sanaullah, Ichiyama, Yusuke, Akwii, Racheal Grace, Tullar, Paul E., Cobos, Christopher, Minchew, Shelby A., Doçi, Colleen L., Zheng, Yi, Kubota, Yoshiaki, Gutkind, J. Silvio, Mikelis, Constantinos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690958/
https://www.ncbi.nlm.nih.gov/pubmed/31406143
http://dx.doi.org/10.1038/s41598-019-48053-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690958/
https://www.ncbi.nlm.nih.gov/pubmed/31406143
http://dx.doi.org/10.1038/s41598-019-48053-z

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