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Protective effect of nobiletin on isolated human islets survival and function against hypoxia and oxidative stress-induced apoptosis
Islets transplantation, as a treatment of type 1 diabetes, faces challenges, including the loss of islets in the process of isolation and pre-transplantation due to cellular stresses-induced apoptosis. Accordingly, the optimization of culture plays a decisive role in the transplantation success. In...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690971/ https://www.ncbi.nlm.nih.gov/pubmed/31406275 http://dx.doi.org/10.1038/s41598-019-48262-6 |