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Danazol mediates collateral sensitivity via STAT3/Myc related pathway in multidrug-resistant cancer cells

Multidrug resistance presents an obstacle in cancer treatment. Among numerous combative strategies, collateral sensitivity (CS) drugs have opened a new avenue to defeat cancer by exploiting selective toxicity against multidrug-resistant (MDR) cancer. In the present study, a clinically used synthetic...

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Detalles Bibliográficos
Autores principales: Chang, Ying-Tzu, Teng, Yu-Ning, Lin, Kun-I, Wang, Charles C. N., Morris-Natschke, Susan L., Lee, Kuo-Hsiung, Hung, Chin-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690972/
https://www.ncbi.nlm.nih.gov/pubmed/31406162
http://dx.doi.org/10.1038/s41598-019-48169-2