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Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy

Mild hypothermia treatment (MHT) improves the neurological function of cardiac arrest (CA) patients, but the exact mechanisms of recovery remain unclear. Herein, we generated a CA and cardiopulmonary resuscitation (CPR) mouse model to elucidate such function. Naïve mice were randomly divided into tw...

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Detalles Bibliográficos
Autores principales: Wei, Hongyan, Yin, Meixian, Lu, Yuanzheng, Yang, Yan, Li, Bo, Liao, Xiao-Xing, Dai, Gang, Jing, Xiaoli, Xiong, Yan, Hu, Chunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690976/
https://www.ncbi.nlm.nih.gov/pubmed/31428461
http://dx.doi.org/10.1038/s41420-019-0209-z