Virus-Specific Secondary Plasma Cells Produce Elevated Levels of High-Avidity Antibodies but Are Functionally Short Lived

Most vaccines aim at inducing durable antibody responses and are designed to elicit strong B cell activation and plasma cell (PC) formation. Here we report characteristics of a recently described secondary PC population that rapidly originates from memory B cells (MBCs) upon challenge with virus-lik...

Descripción completa

Detalles Bibliográficos
Autores principales: Krueger, Caroline C., Thoms, Franziska, Keller, Elsbeth, Vogel, Monique, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691049/
https://www.ncbi.nlm.nih.gov/pubmed/31447844
http://dx.doi.org/10.3389/fimmu.2019.01831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691049/
https://www.ncbi.nlm.nih.gov/pubmed/31447844
http://dx.doi.org/10.3389/fimmu.2019.01831

Ejemplares similares