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TMEM16A Inhibition Preserves Blood–Brain Barrier Integrity After Ischemic Stroke

The inflammatory response plays a pivotal role in Blood–Brain Barrier (BBB) destruction following ischemic brain injury. Enhanced leukocyte adhesion to vascular endothelial cells is an essential event in the inflammatory process. TMEM16A, a newly discovered protein regulating calcium-activated chlor...

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Detalles Bibliográficos
Autores principales: Liu, Pin-yi, Zhang, Zhi, Liu, Yi, Tang, Xue-lian, Shu, Shu, Bao, Xin-yu, Zhang, Yan, Gu, Yue, Xu, Yun, Cao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691060/
https://www.ncbi.nlm.nih.gov/pubmed/31447648
http://dx.doi.org/10.3389/fncel.2019.00360