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NAMPT and NAPRT, Key Enzymes in NAD Salvage Synthesis Pathway, Are of Negative Prognostic Value in Colorectal Cancer

Nicotinamide adenine dinucleotide (NAD) is a profoundly important cofactor in redox reactions. Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase (NAPRT) are key enzymes for NAD salvage biosynthesis pathway, which reciprocally synthesize NAD to supply the main so...

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Detalles Bibliográficos
Autores principales: Li, Xiao-qin, Lei, Jing, Mao, Lin-hong, Wang, Qing-liang, Xu, Feng, Ran, Tao, Zhou, Zhi-hang, He, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691178/
https://www.ncbi.nlm.nih.gov/pubmed/31448236
http://dx.doi.org/10.3389/fonc.2019.00736