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Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing α(Ⅴ)β(3) integrin/FAK/PI3K/Akt signaling activation

PURPOSE: Oxymatrine, an alkaloid extracted from the Chinese herb Sophora flavescens Aiton, possesses anti-inflammatory, anti-immune, anti-hepatic fibrosis, and anti-cancer properties. However, the effects of oxymatrine on epithelial-mesenchymal transition (EMT) of breast cancer cells are still uncle...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Chen, Lin, Zhang, Jing-Yu, Chen, Zong-Yue, Liu, Ting-ting, Zhang, Yan-Yan, Fu, Ling-Yun, Fan, Shuang-Qin, Zhang, Min-Qin, Gan, Shi-quan, Zhang, Nen-ling, Shen, Xiang-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691185/
https://www.ncbi.nlm.nih.gov/pubmed/31496729
http://dx.doi.org/10.2147/OTT.S209056