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TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats

Ischemia-reperfusion injury (IRI) is a notable cause of tissue damage during surgical procedures and a major risk factor in graft dysfunction in liver transplantation. Livers obtained from donors after circulatory death (DCD) are prone to IRI and toll-like receptor 4 (TLR4) serves a prominent role i...

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Detalles Bibliográficos
Autores principales: Zhong, Xiang, Xiao, Qi, Liu, Zhongzhong, Wang, Wei, Lai, Chin-Hui, Yang, Wang, Yue, Pengpeng, Ye, Qifa, Xiao, Jiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691197/
https://www.ncbi.nlm.nih.gov/pubmed/31257518
http://dx.doi.org/10.3892/mmr.2019.10439