MicroRNA-20 induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells

Methylation was suggested to suppress the transcriptional activity of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in hepatocytes. This may be associated with its low replicative activity during the inactive stage of chronic HBV infection; however, the exact mechanisms of methylat...

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Detalles Bibliográficos
Autores principales: Moon, In Young, Choi, Jae Hee, Chung, Jung Wha, Jang, Eun Sun, Jeong, Sook-Hyang, Kim, Jin-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691198/
https://www.ncbi.nlm.nih.gov/pubmed/31257511
http://dx.doi.org/10.3892/mmr.2019.10435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691198/
https://www.ncbi.nlm.nih.gov/pubmed/31257511
http://dx.doi.org/10.3892/mmr.2019.10435

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