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Elevated microRNA-145-5p increases matrix metalloproteinase-9 by activating the nuclear factor-κB pathway in rheumatoid arthritis

The present study explored whether miR-145-5p can aggravate the development and progression of rheumatoid arthritis (RA) by regulating the expression of matrix metalloproteinases (MMPs). ELISAs, reverse transcription-quantitative polymerase chain reaction (RT-qPCR), and western blotting were used to...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxue, Tang, Ke, Wang, Yuanyuan, Chen, Yaqing, Yang, Mengchen, Gu, Chungang, Wang, Jing, Wang, Yi, Yuan, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691224/
https://www.ncbi.nlm.nih.gov/pubmed/31322192
http://dx.doi.org/10.3892/mmr.2019.10499