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Alleviation of sepsis-induced cardiac dysfunction by overexpression of Sestrin2 is associated with inhibition of p-S6K and activation of the p-AMPK pathway

Sepsis-induced myocardial injury is one of the manifestations of multiple organ dysfunction in sepsis. The aim of the present study was to determine the mechanism of alleviation of lipopolysaccharide (LPS)-induced injury on cardiomyocytes by Sestrin2. A sepsis model using LPS injection was construct...

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Detalles Bibliográficos
Autores principales: Wang, Ziwen, Bu, Lin, Yang, Peng, Feng, Shoujie, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691248/
https://www.ncbi.nlm.nih.gov/pubmed/31524263
http://dx.doi.org/10.3892/mmr.2019.10520