Cargando…

ATRA protects skin fibroblasts against UV-induced oxidative damage through inhibition of E3 ligase Hrd1

All-trans retinoic acid (ATRA) can protect fibroblasts against ultraviolet (UV)-induced oxidative damage, however, its underlying molecular mechanism is still unclear. The present study aimed to investigate the role of 3-hydroxy-3-methylglutaryl reductase degradation (Hrd1) in the protective effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Xianye, Qian, Wen, Chen, Fang, Jin, Yi, Wang, Fengdi, Lu, Xiaoyi, Lee, Sae Rom, Su, Dongming, Chen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691267/
https://www.ncbi.nlm.nih.gov/pubmed/31322186
http://dx.doi.org/10.3892/mmr.2019.10450