E3 ubiquitin ligase siah-1 nuclear accumulation is critical for homocysteine-induced impairment of C6 astroglioma cells

Elevated plasma homocysteine (Hcy), known as hyperhomocysteinemia (HHcy), is an independent risk factor for neurodegenerative diseases. Hcy, even at a low concentration, can promote free radical formation and increase oxidative stress, leading to neuronal death, which may be an important mechanism u...

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Detalles Bibliográficos
Autores principales: Tian, Xiangzhu, Gong, Li, Jin, Aiping, Wang, Yu, Zhou, Xiaoyu, Tan, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691270/
https://www.ncbi.nlm.nih.gov/pubmed/31322210
http://dx.doi.org/10.3892/mmr.2019.10449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691270/
https://www.ncbi.nlm.nih.gov/pubmed/31322210
http://dx.doi.org/10.3892/mmr.2019.10449

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