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E3 ubiquitin ligase siah-1 nuclear accumulation is critical for homocysteine-induced impairment of C6 astroglioma cells
Elevated plasma homocysteine (Hcy), known as hyperhomocysteinemia (HHcy), is an independent risk factor for neurodegenerative diseases. Hcy, even at a low concentration, can promote free radical formation and increase oxidative stress, leading to neuronal death, which may be an important mechanism u...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691270/ https://www.ncbi.nlm.nih.gov/pubmed/31322210 http://dx.doi.org/10.3892/mmr.2019.10449 |