In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

Malaria is among the leading causes of death worldwide. The emergence of Plasmodium falciparum resistant strains with reduced sensitivity to the first line combination therapy and suboptimal responses to insecticides used for Anopheles vector management have led to renewed interest in novel therapeu...

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Detalles Bibliográficos
Autores principales: Alberca, Lucas N., Chuguransky, Sara R., Álvarez, Cora L., Talevi, Alan, Salas-Sarduy, Emir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691349/
https://www.ncbi.nlm.nih.gov/pubmed/31448257
http://dx.doi.org/10.3389/fchem.2019.00534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691349/
https://www.ncbi.nlm.nih.gov/pubmed/31448257
http://dx.doi.org/10.3389/fchem.2019.00534

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