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Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer

Rationale: The Polycomb group (PcG) protein EZH2 is implicated in cancer progression due to its frequent overexpression in many cancer types and therefore is a promising therapeutic target. Forkhead box transcription factor-1 (FOXO1) is a tumor suppressor that is often transcriptionally downregulate...

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Detalles Bibliográficos
Autores principales: Ma, Linlin, Yan, Yuqian, Bai, Yang, Yang, Yinhui, Pan, Yunqian, Gang, Xiaokun, Karnes, R. Jeffrey, Zhang, Jun, Lv, Qiubo, Wu, Qiang, Huang, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691386/
https://www.ncbi.nlm.nih.gov/pubmed/31410199
http://dx.doi.org/10.7150/thno.34700