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Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer
Rationale: The Polycomb group (PcG) protein EZH2 is implicated in cancer progression due to its frequent overexpression in many cancer types and therefore is a promising therapeutic target. Forkhead box transcription factor-1 (FOXO1) is a tumor suppressor that is often transcriptionally downregulate...
Autores principales: | Ma, Linlin, Yan, Yuqian, Bai, Yang, Yang, Yinhui, Pan, Yunqian, Gang, Xiaokun, Karnes, R. Jeffrey, Zhang, Jun, Lv, Qiubo, Wu, Qiang, Huang, Haojie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691386/ https://www.ncbi.nlm.nih.gov/pubmed/31410199 http://dx.doi.org/10.7150/thno.34700 |
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