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Multiply clustered gold-based nanoparticles complexed with exogenous pDNA achieve prolonged gene expression in stem cells

Development of a stable and prolonged gene delivery system is a key goal in the gene therapy field. To this end, we designed and fabricated a gene delivery system based on multiply-clustered gold particles that could achieve prolonged gene delivery in stem cells, leading to improved induction of dif...

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Detalles Bibliográficos
Autores principales: Yi, Se Won, Park, Ji Sun, Kim, Hye Jin, Lee, Jung Sun, Woo, Dae Gyun, Park, Keun-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691390/
https://www.ncbi.nlm.nih.gov/pubmed/31410198
http://dx.doi.org/10.7150/thno.34487