Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer

Inhibitor of apoptosis proteins (IAP) are cell death regulators that bind caspases and interfere with apoptotic signalling via death receptors or intrinsic cell death pathways. BIRC4/XIAP is the most potent anti-apoptotic IAP-member and it physically interacts with caspases via its BIR2 and its BIR3...

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Detalles Bibliográficos
Autores principales: Hagenbuchner, Judith, Oberacher, Herbert, Arnhard, Kathrin, Kiechl-Kohlendorfer, Ursula, Ausserlechner, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691393/
https://www.ncbi.nlm.nih.gov/pubmed/31410190
http://dx.doi.org/10.7150/thno.33758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691393/
https://www.ncbi.nlm.nih.gov/pubmed/31410190
http://dx.doi.org/10.7150/thno.33758

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