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Investigating the effect of sildenafil on improving lung function and quality of life in the patients with severe asthma

INTRODUCTION: Phosphodiesterase inhibitors (PDEs) increase intracellular cyclic adenosine monophosphate, which results in a wide range of anti-inflammatory effects and pathologically leads to improve asthma disease. Because no human study has surveyed the effect of PDEs on pulmonary function, except...

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Detalles Bibliográficos
Autores principales: Borsi, Hamid, Raji, Hanieh, Shoushtari, Maryam Haddadzadeh, Tavakol, Heshmatollah, Haghighizadeh, Mohammad Hossein, Mal-Amir, Mehrdad Dargahi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691445/
https://www.ncbi.nlm.nih.gov/pubmed/31463257
http://dx.doi.org/10.4103/jfmpc.jfmpc_334_19