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Drug metabolite synthesis by immobilized human FMO3 and whole cell catalysts
BACKGROUND: Sufficient reference standards of drug metabolites are required in the drug discovery and development process. However, such drug standards are often expensive or not commercially available. Chemical synthesis of drug metabolite is often difficulty due to the highly regio- and stereo-che...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691536/ https://www.ncbi.nlm.nih.gov/pubmed/31405378 http://dx.doi.org/10.1186/s12934-019-1189-7 |