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Drug metabolite synthesis by immobilized human FMO3 and whole cell catalysts

BACKGROUND: Sufficient reference standards of drug metabolites are required in the drug discovery and development process. However, such drug standards are often expensive or not commercially available. Chemical synthesis of drug metabolite is often difficulty due to the highly regio- and stereo-che...

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Detalles Bibliográficos
Autores principales: Gao, Chongliang, Zheng, Tingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691536/
https://www.ncbi.nlm.nih.gov/pubmed/31405378
http://dx.doi.org/10.1186/s12934-019-1189-7