Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2

BACKGROUND: Heparosan is the unsulfated precursor of heparin and heparan sulfate and its synthesis is typically the first step in the production of bioengineered heparin. In addition to its utility as the starting material for this important anticoagulant and anti-inflammatory drug, heparosan is a v...

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Detalles Bibliográficos
Autores principales: Williams, Asher, Gedeon, Kamil S., Vaidyanathan, Deepika, Yu, Yanlei, Collins, Cynthia H., Dordick, Jonathan S., Linhardt, Robert J., Koffas, Mattheos A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691538/
https://www.ncbi.nlm.nih.gov/pubmed/31405374
http://dx.doi.org/10.1186/s12934-019-1187-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691538/
https://www.ncbi.nlm.nih.gov/pubmed/31405374
http://dx.doi.org/10.1186/s12934-019-1187-9

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