Cargando…
Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2
BACKGROUND: Heparosan is the unsulfated precursor of heparin and heparan sulfate and its synthesis is typically the first step in the production of bioengineered heparin. In addition to its utility as the starting material for this important anticoagulant and anti-inflammatory drug, heparosan is a v...
Autores principales: | Williams, Asher, Gedeon, Kamil S., Vaidyanathan, Deepika, Yu, Yanlei, Collins, Cynthia H., Dordick, Jonathan S., Linhardt, Robert J., Koffas, Mattheos A. G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691538/ https://www.ncbi.nlm.nih.gov/pubmed/31405374 http://dx.doi.org/10.1186/s12934-019-1187-9 |
Ejemplares similares
-
In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2
por: Chavaroche, Anaïs A. E., et al.
Publicado: (2009) -
Synthesis of heparosan oligosaccharides by Pasteurella multocida PmHS2 single-action transferases
por: Chavaroche, Anaïs A. E., et al.
Publicado: (2011) -
RNA Aptamers with Specificity for Heparosan and Chondroitin
Glycosaminoglycans
por: Kizer, Megan, et al.
Publicado: (2018) -
A Revised Structure for the Glycolipid Terminus of Escherichia coli K5 Heparosan Capsular Polysaccharide
por: Yan, Lufeng, et al.
Publicado: (2020) -
New insight into chondroitin and heparosan-like capsular polysaccharide synthesis by profiling of the nucleotide sugar precursors
por: Restaino, Odile Francesca, et al.
Publicado: (2017)