APLN promotes hepatocellular carcinoma through activating PI3K/Akt pathway and is a druggable target

Background: The pathogenesis of hepatocellular carcinoma (HCC) is a multistep process contributed by the accumulation of molecular alterations. We identified Apelin (APLN) as an outlier gene up-regulated in hepatocellular carcinoma (HCC) through RNA-Seq and microarray analysis. We aimed to investiga...

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Detalles Bibliográficos
Autores principales: Chen, Huarong, Wong, Chi-Chun, Liu, Dabin, Go, Minnie Y.Y., Wu, Bin, Peng, Sui, Kuang, Ming, Wong, Nathalie, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691573/
https://www.ncbi.nlm.nih.gov/pubmed/31410213
http://dx.doi.org/10.7150/thno.34713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691573/
https://www.ncbi.nlm.nih.gov/pubmed/31410213
http://dx.doi.org/10.7150/thno.34713

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