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Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model

The neuropathological hallmarks of Alzheimer's disease include amyloid plaques and neurofibrillary tangles. Tau pathology correlates well with impaired neuronal activity and dementia. Focused ultrasound coupled with systemic administration of microbubbles has previously been shown to open the b...

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Detalles Bibliográficos
Autores principales: Karakatsani, Maria Eleni, Kugelman, Tara, Ji, Robin, Murillo, Maria, Wang, Shutao, Niimi, Yusuke, Small, Scott A., Duff, Karen E., Konofagou, Elisa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691580/
https://www.ncbi.nlm.nih.gov/pubmed/31410223
http://dx.doi.org/10.7150/thno.28717