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Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model
The neuropathological hallmarks of Alzheimer's disease include amyloid plaques and neurofibrillary tangles. Tau pathology correlates well with impaired neuronal activity and dementia. Focused ultrasound coupled with systemic administration of microbubbles has previously been shown to open the b...
Autores principales: | Karakatsani, Maria Eleni, Kugelman, Tara, Ji, Robin, Murillo, Maria, Wang, Shutao, Niimi, Yusuke, Small, Scott A., Duff, Karen E., Konofagou, Elisa E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691580/ https://www.ncbi.nlm.nih.gov/pubmed/31410223 http://dx.doi.org/10.7150/thno.28717 |
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