SphK1 functions downstream of IGF-1 to modulate IGF-1-induced EMT, migration and paclitaxel resistance of A549 cells: A preliminary in vitro study

Insulin-like growth factor-1 (IGF-1) -induced epithelial-mesenchymal transition (EMT) plays a key role in the metastasis and drug resistance of non-small cell lung cancer (NSCLC). Sphingosine kinase-1 (SphK1) is also involved in EMT of NSCLC. However, the interaction between SphK1 and IGF-1 in the E...

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Detalles Bibliográficos
Autores principales: Wu, Xingping, Wu, Qibiao, Zhou, Xiqiao, Huang, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691691/
https://www.ncbi.nlm.nih.gov/pubmed/31413745
http://dx.doi.org/10.7150/jca.32646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691691/
https://www.ncbi.nlm.nih.gov/pubmed/31413745
http://dx.doi.org/10.7150/jca.32646

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