Preclinical Targeting of Human Acute Myeloid Leukemia Using CD4-specific Chimeric Antigen Receptor (CAR) T Cells and NK Cells

Acute myeloid leukemia (AML) is an aggressive malignancy lacking targeted therapy due to shared molecular and transcriptional circuits as well as phenotypic markers with normal hematopoietic stem cells (HSCs). Identifying leukemia specific markers expressed on AML or AML subtypes for therapeutic tar...

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Detalles Bibliográficos
Autores principales: Salman, Huda, Pinz, Kevin G., Wada, Masayuki, Shuai, Xiao, Yan, Lulu E., Petrov, Jessica C., Ma, Yupo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691696/
https://www.ncbi.nlm.nih.gov/pubmed/31413761
http://dx.doi.org/10.7150/jca.28952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691696/
https://www.ncbi.nlm.nih.gov/pubmed/31413761
http://dx.doi.org/10.7150/jca.28952

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