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Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells

Proteasome inhibition is a promising strategy for the treatment of multiple myeloma; unfortunately, this disease is often associated with an increasing chemoresistance. One novel approach may be to target the immunoproteasome, a proteasomal isoform mainly present in cells of hematopoietic origin. We...

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Detalles Bibliográficos
Autores principales: Ettari, Roberta, Pallio, Giovanni, Pizzino, Gabriele, Irrera, Natasha, Zappalà, Maria, Maiorana, Santina, Di Chio, Carla, Altavilla, Domenica, Squadrito, Francesco, Bitto, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691773/
https://www.ncbi.nlm.nih.gov/pubmed/31307247
http://dx.doi.org/10.1080/14756366.2019.1594802