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Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells
Proteasome inhibition is a promising strategy for the treatment of multiple myeloma; unfortunately, this disease is often associated with an increasing chemoresistance. One novel approach may be to target the immunoproteasome, a proteasomal isoform mainly present in cells of hematopoietic origin. We...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691773/ https://www.ncbi.nlm.nih.gov/pubmed/31307247 http://dx.doi.org/10.1080/14756366.2019.1594802 |