Cargando…

Epigenetic mechanisms underlying the effects of triptolide and tripchlorolide on the expression of neuroligin-1 in the hippocampus of APP/PS1 transgenic mice

Context: Neuroligin-1 (NLGN1) is a cell adhesion protein located on the excitatory postsynaptic membrane. β-Amyloid (Aβ)-induced neuroinflammation decreases NLGN1 expression through epigenetic mechanisms. Triptolide (T10) and tripchlorolide (T4) exert protective effects on synapses in Alzheimer'...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xiaomei, Yang, Baolin, Yu, Hao, Hu, Xiaoling, Nie, Jing, Wan, Bin, Zhang, Ming, Lü, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691810/ https://www.ncbi.nlm.nih.gov/pubmed/31311385 http://dx.doi.org/10.1080/13880209.2019.1629463

Ejemplares similares

The effects of treadmill exercise on autophagy in hippocampus of APP/PS1 transgenic mice
por: Zhao, Na, et al.
Publicado: (2018)

Effects of triptolide on hippocampal microglial cells and astrocytes in the APP/PS1 double transgenic mouse model of Alzheimer's disease
por: Li, Jian-ming, et al.
Publicado: (2016)

Tripchlorolide attenuates β-amyloid generation by inducing NEP activity in N2a/APP695 cells
por: Zeng, Yuqi, et al.
Publicado: (2021)

Tripchlorolide induces cell death in lung cancer cells by autophagy
por: CHEN, LIMIN, et al.
Publicado: (2011)

Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease
por: Hosseinpour Mashkani, Seyed Mostafa, et al.
Publicado: (2023)

Exercise-Induced Neuroprotection of Hippocampus in APP/PS1 Transgenic Mice via Upregulation of Mitochondrial 8-Oxoguanine DNA Glycosylase
por: Bo, Hai, et al.
Publicado: (2014)

Behavioral Changes and Hippocampus Glucose Metabolism in APP/PS1 Transgenic Mice via Electro-acupuncture at Governor Vessel Acupoints
por: Cao, Jin, et al.
Publicado: (2017)

Effects of (−)Epicatechin on the Pathology of APP/PS1 Transgenic Mice
por: Zeng, Yue-Qin, et al.
Publicado: (2014)

Improvement of Electroacupuncture on APP/PS1 Transgenic Mice in Spatial Learning and Memory Probably due to Expression of Aβ and LRP1 in Hippocampus
por: Wang, Xin, et al.
Publicado: (2016)

Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP(swe)/PS1(ΔE9) Transgenic Mice
por: Myhre, Christa Løth, et al.
Publicado: (2019)

Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice
por: Yang, Wenjuan, et al.
Publicado: (2018)

Tripchlorolide May Improve Spatial Cognition Dysfunction and Synaptic Plasticity after Chronic Cerebral Hypoperfusion
por: Yao, Zhao-Hui, et al.
Publicado: (2019)

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus
por: Torres, Manuel, et al.
Publicado: (2012)

Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice
por: Wang, Zigao, et al.
Publicado: (2017)

Specific Neuroligin3–αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus
por: Uchigashima, Motokazu, et al.
Publicado: (2020)

Deposition of BACE-1 Protein in the Brains of APP/PS1 Double Transgenic Mice
por: Luo, Gang, et al.
Publicado: (2016)

Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins
por: Liu, Xing, et al.
Publicado: (2022)

Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice
por: Chen, Lizhi, et al.
Publicado: (2019)

Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice
por: Dickey, Chad A, et al.
Publicado: (2005)

Tanshinone IIA Alleviates the AD Phenotypes in APP and PS1 Transgenic Mice
por: Li, Fengling, et al.
Publicado: (2016)

Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signaling
por: Li, Lei, et al.
Publicado: (2020)

Neuroligin-1 is altered in the hippocampus of Alzheimer’s disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers
por: Dufort-Gervais, Julien, et al.
Publicado: (2020)

Vaccine Development to Treat Alzheimer's Disease Neuropathology in APP/PS1 Transgenic Mice
por: Carrera, Iván, et al.
Publicado: (2012)

Electroacupuncture decreases cognitive impairment and promotes neurogenesis in the APP/PS1 transgenic mice
por: Li, Xuying, et al.
Publicado: (2014)

Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders
por: Zhang, Zhenzhen, et al.
Publicado: (2022)

High Dietary Iron Disrupts Iron Homeostasis and Induces Amyloid-β and Phospho-τ Expression in the Hippocampus of Adult Wild-Type and APP/PS1 Transgenic Mice
por: Chen, Min, et al.
Publicado: (2019)

Effects of proton radiation on evoked and spontaneous neuronal activity in the hippocampus of APP/PSEN1 transgenic mice
por: Rudobeck, Emil, et al.
Publicado: (2014)

Nanoscale alterations in GABA(B) receptors and GIRK channel organization on the hippocampus of APP/PS1 mice
por: Martín-Belmonte, Alejandro, et al.
Publicado: (2022)

Expression of tiRNA and tRF in APP/PS1 transgenic mice and the change of related proteins expression
por: Lu, Honglin, et al.
Publicado: (2021)

Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model
por: Wu, Di, et al.
Publicado: (2021)

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice
por: Hiltunen, Mikko, et al.
Publicado: (2012)

Synaptic Changes in the Dentate Gyrus of APP/PS1 Transgenic Mice Revealed by Electron Microscopy
por: Alonso-Nanclares, Lidia, et al.
Publicado: (2013)

Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model
por: Yang, Seung-Hoon, et al.
Publicado: (2015)

Effects and Mechanism of Huannao Yicong Decoction Extract on the Ethology of Transgenic APP/PS1 Mice
por: Liu, Meixia, et al.
Publicado: (2017)

Untargeted lipidomics reveals progression of early Alzheimer’s disease in APP/PS1 transgenic mice
por: Zhang, Xueju, et al.
Publicado: (2020)

Effects of Peppermint Essential Oil on Learning and Memory Ability in APP/PS1 Transgenic Mice
por: Lv, Xiaofan, et al.
Publicado: (2022)

Treadmill Exercise Ameliorates Adult Hippocampal Neurogenesis Possibly by Adjusting the APP Proteolytic Pathway in APP/PS1 Transgenic Mice
por: Yu, Haizhen, et al.
Publicado: (2021)

Neuropeptide S Ameliorates Cognitive Impairment of APP/PS1 Transgenic Mice by Promoting Synaptic Plasticity and Reducing Aβ Deposition
por: Zhao, Peng, et al.
Publicado: (2019)

Effects of Curculigoside on Memory Impairment and Bone Loss via Anti-Oxidative Character in APP/PS1 Mutated Transgenic Mice
por: Zhao, Lu, et al.
Publicado: (2015)

Immune senescence in aged APP/PS1 mice
por: Abdelmoaty, Mai M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1d4p26sh8ok8ioekmecdpnm2d9