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Age-Based Dynamics of a Stable Circulating Cd8 T Cell Repertoire Component
T-cell memory to pathogens can be envisioned as a receptor-based imprint of the pathogenic environment on the naïve repertoire of clonotypes. Recurrent exposures to a pathogen inform and reinforce memory, leading to a mature state. The complexity and temporal stability of this system in man is only...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691812/ https://www.ncbi.nlm.nih.gov/pubmed/31447830 http://dx.doi.org/10.3389/fimmu.2019.01717 |