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Nrf2 participates in mechanisms for reducing the toxicity and enhancing the antitumour effect of Radix Tripterygium wilfordii to S180-bearing mice by herbal-processing technology

Context: Radix Tripterygium wilfordii Hook. f. (Celastraceae) (LGT) has outstanding curative efficacy; however, side effects include high toxicity, particularly hepatotoxicity and nephrotoxicity. Objective: To investigate detoxification mechanisms of LGT through processing separately with each of th...

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Detalles Bibliográficos
Autores principales: Wang, Jun-Ming, Li, Jin-Yang, Cai, Hong, Chen, Rong-Xing, Zhang, Yue-Yue, Zhang, Lu-Lu, Cui, Ying, Cheng, Yong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691819/
https://www.ncbi.nlm.nih.gov/pubmed/31280667
http://dx.doi.org/10.1080/13880209.2019.1634106